China (Mainland)
Pazopanib Hydrochloride (CAS: 635702-64-6) CAS NO.439081-18-2
- Min.Order: 100 Gram
- Payment Terms: L/C,T/T,MoneyGram
- Product Details
Keywords
- raw material
- API
- anticancer
Quick Details
- ProName: Pazopanib Hydrochloride (CAS: 635702-6...
- CasNo: 439081-18-2
- Application: Anticancer Raw Material
- DeliveryTime: 7-12 days
- PackAge: Aluminum Foil Bag or Fiber Drum
- Port: Shenzhen
- ProductionCapacity: 100 Metric Ton/Month
- Purity: 99
- Transportation: EMS
- LimitNum: 100 Gram
Superiority
Pazopanib Hydrochloride (CAS: 635702-64-6)
Chemical Information
Product Name Pazopanib Hydrochloride
Molecular Formula C21H24ClN7O2S
Molecular Weight 473.98
Purity: 99%+
Product Specifications: Pharmaceutical Grade
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT
Brand: Newbio Pharm-Tech
Description
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
Pazopanib potently inhibits VEGF-induced phosphorylation of VEGFR2 in HUVEC cells with IC50 of 8 nM. Pazopanib shows dose-dependent growth inhibition in all synovial sarcoma cell lines including SYO-1 and HS-SY-II cells.
Details
Pazopanib Hydrochloride (CAS: 635702-64-6)
Chemical Information
Product Name Pazopanib Hydrochloride
Molecular Formula C21H24ClN7O2S
Molecular Weight 473.98
Purity: 99%+
Product Specifications: Pharmaceutical Grade
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT
Brand: Newbio Pharm-Tech
Description
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
Pazopanib potently inhibits VEGF-induced phosphorylation of VEGFR2 in HUVEC cells with IC50 of 8 nM. Pazopanib shows dose-dependent growth inhibition in all synovial sarcoma cell lines including SYO-1 and HS-SY-II cells.